Apixaban is a type of medicine known as an anticoagulant. It makes your blood flow through your veins more easily, which means your blood is less likely to make blood clots. It’s used to treat people who have had a health problem caused by a blood clot, such as: a blood clot in the leg (deep vein thrombosis, or DVT)
- bleeding gums.
- heavy vaginal bleeding.
- red, pink, or brown urine.
- red or black, tarry stools.
- coughing up or vomiting blood or material that looks like coffee grounds.
- swelling or joint pain.
Dosage and strength
Apixaban comes as 2.5mg and 5mg tablets.
Your dose of apixaban depends on why you’re taking it. If you’re unsure what dose you need to take, check with your doctor or pharmacist.
The usual dose in adults if you:
- have a heart condition called atrial fibrillation is one 5mg tablet, taken twice a day. Your doctor may prescribe a lower dose of one 2.5mg tablet twice a day if you’re over 80 years old, weigh less than 60kg (9st 6lb), or have kidney disease and are at higher risk of bleeding
- have recently had a blood clot (within the last 6 months) is two 5mg tablets taken twice a day, for the first 7 days. After that, you’ll take one 5mg tablet twice a day
- need to reduce the risk of a future blood clot is one 2.5mg tablet taken twice a day
- have had a hip or knee replacement is one 2.5mg tablet, taken twice a day. You’ll usually take your first dose 12 to 24 hours after surgery
How to take it
You’ll usually take apixaban tablets twice a day. Try to take it at the same time every day.
Swallow the tablet with a drink of water. Apixaban can be taken with or without food.
You can crush apixaban tablets and mix them with water, apple juice or apple purée. Swallow this mixture straight away.
How long to take it for
How long you need to take apixaban will depend on why you’re taking it. If you have had:
- knee replacement surgery, you’ll usually take it for 10 to 14 days
- a hip replacement, you’ll usually take it for 32 to 38 days
- a blood clot (DVT or pulmonary embolism), you’ll usually take it for at least 3 months
Depending on what caused the blood clot, you might need to take it for longer.
If you have a heart problem like atrial fibrillation, you might need to take apixaban long term or even for the rest of your life.
Do not stop taking apixaban without talking to your doctor.
Apixaban is used to treat or prevent deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. This medicine is used for several days after hip or knee replacement surgery while you are unable to walk. It is during this time that blood clots are most likely to form.
Apixaban is also used to prevent stroke and blood clots in patients with certain heart rhythm problem (eg, nonvalvular atrial fibrillation).
Apixaban is a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and helps preventing harmful clots from forming in the blood vessels.
This medicine is available only with your doctor’s prescription.
This product is available in the following dosage forms: